IGF1R CLIA Kit for Bovine(Bos taurus) | EIAab.comIGF1R CLIA Kit for Bovine(Bos taurus)

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IGF1R (Gene name),

Insulin-like growth factor 1 receptor (Protein name ), IGF1R_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

IGF1R;

Protein name:

Insulin-like growth factor 1 receptor;

Alternative:

Insulin-like growth factor I receptor(IGF-I receptor);

CD:

CD221;

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chain carries the kinase domain. Interacts with PIK3R1 and with the PTB/PID domains of IRS1 and SHC1 in vitro when autophosphorylated on tyrosine residues. Forms a hybrid receptor with INSR, the hybrid is a tetramer consisting of 1 alpha chain and 1 beta chain of INSR and 1 alpha chain and 1 beta chain of IGF1R. Interacts with ARRB1 and ARRB2. Interacts with GRB10. Interacts with GNB2L1/RACK1.

Function:

This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

640

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

640:

GPGPGVLVLR | ASFDERQPYA | HMNGGRKNER | ALPLPQSSTC |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q05688

STRING:

9913.ENSBTAP00000028690

KEGG:

bta:281848

UniGene:

Bt.105919

UniGene:

Bt.12759

String:

Q05688

Pfam:

PF00041

Uniprot:

Q05688

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ELISA Kit for Bovine Insulin-like growth factor 1 receptor

Cat.:

E1200h

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96T

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ELISA Kit for Bovine Insulin-like growth factor 1 receptor

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E1200p

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96T

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ELISA Kit for Bovine Insulin-like growth factor 1 receptor

Cat.:

E1200b

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96T

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ELISA Kit for Bovine Insulin-like growth factor 1 receptor

Cat.:

E1200r

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96T

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ELISA Kit for Bovine Insulin-like growth factor 1 receptor

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E1200m

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96T

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CLIA Kit for Bovine Insulin-like growth factor 1 receptor

MSDS:

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CLIA Kit for Bovine Insulin-like growth factor 1 receptor

Cat.:

U1200p

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MSDS:

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Packing:

96T

CLIA Kit for Bovine Insulin-like growth factor 1 receptor

Cat.:

U1200m

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MSDS:

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Packing:

96T

CLIA Kit for Bovine Insulin-like growth factor 1 receptor

Cat.:

U1200h

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Bovine Insulin-like growth factor 1 receptor

Cat.:

U1200r

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96T

Polyclonal Antibody for Bovine Insulin-like growth factor 1 receptor

Cat.:

P1200Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine Insulin-like growth factor 1 receptor

Cat.:

P1200Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine Insulin-like growth factor 1 receptor

Cat.:

P1200Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Bovine Insulin-like growth factor 1 receptor

Monoclonal Antibody for Bovine Insulin-like growth factor 1 receptor

Protein for Bovine Insulin-like growth factor 1 receptor

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Cloning and characterization of a cDNA encoding the beta-subunit of the bovine insulin-like growth factor-1 receptor."
Sneyers M. , Kettmann R. , Massart S. , Renaville R. , Burny A. , Portetelle D.
DNA Seq.1:405-406(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Kidney.

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